Obesity is one of the most critical nutritional diseases in today’s world. While research behind obesity intervention have, for the past few decades, circumnavigated topics like diet and workout programs, modern medicine has proven that medical interventions, in conjunction with diet and exercise, can drastically aid in the treatment of obesity. A new generation of anti-obesity drugs, namely glucagon-like peptide 1 (GLP-1) receptor agonists, have garnered positive results with patients living with obesity. This brief will focus on the relationship between nutrition, obesity, and weight management with patients with chronic diseases, and the recent medical interventions to combat today’s obesity crisis.